RNASE1 Antibody - #DF14814

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Product: RNASE1 Antibody
Catalog: DF14814
Description: Rabbit polyclonal antibody to RNASE1
Application: IHC IF/ICC
Reactivity: Human
Mol.Wt.: 18kD(Calculated).
Uniprot: P07998

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
RNASE1 Antibody detects endogenous levels of RNASE1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HP-RNase; Pancreatic ribonuclease; Rib 1; RIB-1; Rib1; Ribonuclease 1; Ribonuclease A; Ribonuclease a family 1; Ribonuclease pancreatic; Ribonuclease RNase A family 1; Ribonuclease RNase A family 1 pancreatic; RNAS1_HUMAN; RNase 1; RNase A; RNase UpI-1; Rnase1; RNAseA;

Immunogens

Immunogen:

A synthesized peptide derived from human RNASE1.

Uniprot:

P07998(RNAS1_HUMAN) >>Visit HPA database.

Gene(ID):
RNASE1(6035)
Expression:
P07998 RNAS1_HUMAN:

Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion).

Sequence:
MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST

Research Backgrounds

Function:

Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.

PTMs:

N-linked glycans are of complex type.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion).

Subunit Structure:

Monomer. Interacts with and forms tight 1:1 complexes with RNH1. Dimerization of two such complexes may occur. Interaction with RNH1 inhibits this protein.

Family&Domains:

Belongs to the pancreatic ribonuclease family.

Restrictive clause

 

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