ZPBP Antibody - #DF14866

(2)  
Product: ZPBP Antibody
Catalog: DF14866
Description: Rabbit polyclonal antibody to ZPBP
Application: IHC IF/ICC
Reactivity: Human
Mol.Wt.: 40kD(Calculated).
Uniprot: Q9BS86

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
ZPBP Antibody detects endogenous levels of ZPBP.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

4930486K01Rik; FLJ9322; Iam38; OTTHUMP00000208840; OTTMUSP00000008129; RP23-446K7.1; Sp38; Zona pellucida binding protein; Zona pellucida binding protein 1; ZPBP;

Immunogens

Immunogen:

A synthesized peptide derived from human ZPBP.

Uniprot:

Q9BS86(ZPBP1_HUMAN) >>Visit HPA database.

Gene(ID):
ZPBP(11055)
Expression:
Q9BS86 ZPBP1_HUMAN:

Expressed specifically in testis.

Sequence:
MEAFALGPARRGRRRTRAAGSLLSRAAILLFISAFLVRVPSSVGHLVRLPRAFRLTKDSVKIVGSTSFPVKAYVMLHQKSPHVLCVTQQLRNAELIDPSFQWYGPKGKVVSVENRTAQITSTGSLVFQNFEESMSGIYTCFLEYKPTVEEIVKRLQLKYAIYAYREPHYYYQFTARYHAAPCNSIYNISFEKKLLQILSKLLLDLSCEISLLKSECHRVKMQRAGLQNELFFAFSVSSLDTEKGPKRCTDHNCEPYKRLFKAKNLIERFFNQQVEILGRRAEQLPQIYYIEGTLQMVWINRCFPGYGMNVQQHPKCPECCVICSPGSYNPRDGIHCLQCNSSLVYGAKTCL

Research Backgrounds

Function:

Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity).

PTMs:

N-glycosylated.

Subcellular Location:

Cytoplasmic vesicle>Secretory vesicle>Acrosome membrane>Peripheral membrane protein. Secreted.
Note: First localized in acrosome granule, later migrates to the inner and outer acrosomal membrane. Released after the acrosomal reaction.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed specifically in testis.

Family&Domains:

Belongs to the zona pellucida-binding protein Sp38 family.

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