ZC4H2 Antibody - #DF14896

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Product: ZC4H2 Antibody
Catalog: DF14896
Description: Rabbit polyclonal antibody to ZC4H2
Application: WB
Reactivity: Human, Mouse
Mol.Wt.: 26kD(Calculated).
Uniprot: Q9NQZ6

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ZC4H2 Antibody detects endogenous levels of ZC4H2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HCA127; Hepatocellular carcinoma-associated antigen 127; KIAA1166; OTTHUMP00000023432; Zc4h2; ZC4H2_HUMAN; Zinc finger C4H2 domain containing; Zinc finger C4H2 domain-containing protein;

Immunogens

Immunogen:

A synthesized peptide derived from human ZC4H2.

Uniprot:

Q9NQZ6(ZC4H2_HUMAN) >>Visit HPA database.

Gene(ID):
ZC4H2(55906)
Expression:
Q9NQZ6 ZC4H2_HUMAN:

Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle (PubMed:23623388). Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord (PubMed:26056227).

Sequence:
MADEQEIMCKLESIKEIRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTRQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE

Research Backgrounds

Function:

Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.

Subcellular Location:

Cytoplasm. Nucleus. Cell junction>Synapse>Postsynaptic cell membrane.
Note: Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.

Restrictive clause

 

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