DCUN1D2 Antibody - #DF14901
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
C13orf17; DCN1 like protein 2; DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae); DCN1-like protein 2; DCNL2_HUMAN; DCUN1 domain-containing protein 2; DCUN1D2; DCUN1L2; Defective in cullin neddylation protein 1-like protein 2; FLJ10704; FLJ20092; OTTHUMP00000018776;
Immunogens
A synthesized peptide derived from human DCUN1D2.
- Q6PH85 DCNL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLIDDFVEYARPVVTGGKRSLF
Research Backgrounds
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
The DCUN1 domain, also known as PONY domain mediates recognition of the N-terminally acetylated NEDD8-conjugating E2 enzyme.
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