PPP1R18 Antibody - #DF14927

(2)  
Product: PPP1R18 Antibody
Catalog: DF14927
Description: Rabbit polyclonal antibody to PPP1R18
Application: IHC
Reactivity: Human
Mol.Wt.: 68kD(Calculated).
Uniprot: Q6NYC8

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
PPP1R18 Antibody detects endogenous levels of PPP1R18.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HKMT1098; KIAA1949; PPP1R18; Protein phosphatase 1 F actin cytoskeleton targeting subunit; Protein phosphatase 1 regulatory subunit 18;

Immunogens

Immunogen:

A synthesized peptide derived from human PPP1R18.

Uniprot:

Q6NYC8(PPR18_HUMAN) >>Visit HPA database.

Gene(ID):
PPP1R18(170954)
Expression:
Q6NYC8 PPR18_HUMAN:

Isoform 4 is predominantly expressed in leukocytes and spleen.

Sequence:
MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGLRTKALIVDESCRR

Research Backgrounds

Function:

May target protein phosphatase 1 to F-actin cytoskeleton.

May target protein phosphatase 1 to F-actin cytoskeleton.

Subcellular Location:

Cytoplasm>Cytoskeleton.

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Isoform 4 is predominantly expressed in leukocytes and spleen.

Subunit Structure:

Interacts with Protein phosphatase 1 (PP1).

Restrictive clause

 

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