Product: RSRC1 Antibody
Catalog: DF14990
Description: Rabbit polyclonal antibody to RSRC1
Application: IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 39kD(Calculated).
Uniprot: Q96IZ7

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RSRC1 Antibody detects endogenous levels of RSRC1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1200013F24Rik; Arginine/serine rich coiled coil 1; Arginine/serine-rich coiled-coil protein 1; BM 011; MGC103357; MGC12197; OTTHUMP00000213444; OTTHUMP00000213446; OTTHUMP00000213451; RGD1304968; Rsrc1; RSRC1_HUMAN; Serine/Arginine-related protein 53; SFRS21; Splicing factor arginine/serine rich 21; SRrp53;

Immunogens

Immunogen:

A synthesized peptide derived from human RSRC1.

Uniprot:
Gene(ID):
Expression:
Q96IZ7 RSRC1_HUMAN:

Widely expressed. Expressed in brain, spinal cord, cerebellum.

Sequence:
MGRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIEAIESDSFVQQTFRSSKEVKKSVEPSEVKQATSTSGPASAVADPPSTEKEIDPTSIPTAIKYQDDNSLAHPNLFIEKADAEEKWFKRLIALRQERLMGSPVA

Research Backgrounds

Function:

Has a role in alternative splicing and transcription regulation. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing.

PTMs:

Phosphorylated.

Subcellular Location:

Nucleus. Nucleus speckle. Cytoplasm.
Note: Shuttles between the nucleus and cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Expressed in brain, spinal cord, cerebellum.

Subunit Structure:

Interacts (via Arg/Ser-rich domain) with LUC7L3, RBM39 and RSF1.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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