Product: AIDA Antibody
Catalog: DF15062
Description: Rabbit polyclonal antibody to AIDA
Application: IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 35kD(Calculated).
Uniprot: Q96BJ3

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
AIDA Antibody detects endogenous levels of AIDA.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2610208M17Rik; AIDA; AIDA_HUMAN; Axin interaction partner and dorsalization antagonist; Axin interactor; Axin interactor dorsalization associated protein; Axin interactor, dorsalization associated; C1orf80; Chromosome 1 open reading frame 80; dorsalization-associated protein; RP11-378J18.7; UPF0491 protein C1orf80;

Immunogens

Immunogen:

A synthesized peptide derived from human AIDA.

Uniprot:
Gene(ID):
Expression:
Q96BJ3 AIDA_HUMAN:

Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.

Sequence:
MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE

Research Backgrounds

Function:

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).

Tissue Specificity:

Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.

Subunit Structure:

Interacts with AXIN1.

Family&Domains:

Belongs to the AIDA family.

Restrictive clause

 

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