TXNDC17 Antibody - #DF15119

(3)  
Product: TXNDC17 Antibody
Catalog: DF15119
Description: Rabbit polyclonal antibody to TXNDC17
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 14kD(Calculated).
Uniprot: Q9BRA2

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
TXNDC17 Antibody detects endogenous levels of TXNDC17.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

14 kDa thioredoxin-related protein; Protein 42-9-9; Thioredoxin domain-containing protein 17; Thioredoxin-like protein 5; TRP14; TXD17_HUMAN; TXNDC17;

Immunogens

Immunogen:

A synthesized peptide derived from human TXNDC17.

Uniprot:

Q9BRA2(TXD17_HUMAN) >>Visit HPA database.

Gene(ID):
TXNDC17(84817)
Expression:
Q9BRA2 TXD17_HUMAN:

Ubiquitously expressed in cell lines.

Sequence:
MARYEEVSVSGFEEFHRAVEQHNGKTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRKNLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED

Research Backgrounds

Function:

Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.

PTMs:

The oxidized protein is reduced by TRXR1.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitously expressed in cell lines.

Subunit Structure:

Interacts with TRXR1 and DYNLL1/DNCL1.

Family&Domains:

Belongs to the thioredoxin family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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