SHCBP1L Antibody | Affinity Biosciences

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SHCBP1L Antibody - DF15172 at 1/100 staining mouse testis tissue by IHC-P.

Product:	SHCBP1L Antibody
Catalog:	DF15172
Description:	Rabbit polyclonal antibody to SHCBP1L
Application:	IHC
Reactivity:	Human, Mouse
Mol.Wt.:	73kD(Calculated).
Uniprot:	Q9BZQ2

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Clonality:

Polyclonal

Specificity:

SHCBP1L Antibody detects endogenous levels of SHCBP1L.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

1700012A16Rik; C1orf14; GE36; RGD1305609; RP5-1133A12.2; SHC binding and spindle associated 1 like; SHC SH2 domain-binding protein 1-like protein; SHCBP1L; SHP1L_HUMAN;

Immunogens

Immunogen:

A synthesized peptide derived from human SHCBP1L.

Uniprot:

Q9BZQ2(SHP1L_HUMAN) >>Visit HPA database.

Gene(ID):

SHCBP1L(81626)

Expression:

Q9BZQ2 SHP1L_HUMAN:

Expressed in spermatocytes and elongating spermatids inside the seminiferous tubules (at protein level) (PubMed:24557841). Testis-specific (PubMed:11318611, PubMed:24557841).

Sequence:

Q9BZQ2 SHP1L_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MASGSKASVPADSFRTISPDRRGEKSASAVSGDTAAATTLKGTAIPVRSVVASPRPVKGKAGRETARLRLQRLPAAQAEDTGEAAAAAAEEPLLPVPEDEEEAQPLPPVCVSRMRGMWRDEKVSLYCDEVLQDCKAEDADEVMGKYLSEKLKLKDKWLGVWKTNPSVFFVKYEEASIPFVGILVEVTCEPYQDSSSRFKVTVSVAEPFSSNIANIPRDLVDEILEELEHSVPLLEVYPVEGQDTDIHVIALALEVVRFFYDFLWRDWDDEESCENYTALIEERINLWCDIQDGTIPGPIAQRFKKTLEKYKNKRVELIEYQSNIKEDPSAAEAVECWKKYYEIVMLCGLLKMWEDLRLRVHGPFFPRILRRRKGKREFGKTITHIVAKMMTTEMIKDLSSDTLLQQHGDLDLALDNCYSGDTVIIFPGEYQAANLALLTDDIIIKGVGKREEIMITSEPSRDSFVVSKADNVKLMHLSLIQQGTVDGIVVVESGHMTLENCILKCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILERNEIHHCNNLRTSNSSKSTLGGVNMKVLPAPKLKMTNNHIYSNKGYGVSILQPMEQFFIVAEEALNKRASSGDKKDDKMLFKVMQNLNLEMNNNKIEANVKGDIRIVTS

Research Backgrounds

Q9BZQ2_SHP1L_HUMAN

Function:

Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells.

Subcellular Location:

Cytoplasm>Cytoskeleton>Spindle.
Note: Colocalizes with alpha tubulin during meiosis. Colocalizes with HSPA2 at spindle during the meiosis process.

Tissue Specificity:

Expressed in spermatocytes and elongating spermatids inside the seminiferous tubules (at protein level). Testis-specific.

Subunit Structure:

Interacts with HSPA2; this interaction may promote the recruitment of HSPA2 to the spindle.

Restrictive clause

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For Research Use Only.
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SHCBP1L Antibody - #DF15172