Product: PPTC7 Antibody
Catalog: DF15198
Description: Rabbit polyclonal antibody to PPTC7
Application: ELISA(peptide)
Reactivity: Human, Mouse
Mol.Wt.: 33kD(Calculated).
Uniprot: Q8NI37

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
PPTC7 Antibody detects endogenous levels of PPTC7.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

pptc7; PPTC7_HUMAN; Protein phosphatase PTC7 homolog; PTC7 protein phosphatase homolog (S. cerevisiae); T-cell activation protein phosphatase 2C; T-cell activation protein phosphatase 2C-like; TA-PP2C; TAPP2C;

Immunogens

Immunogen:

A synthesized peptide derived from human PPTC7.

Uniprot:
Gene(ID):
Expression:
Q8NI37 PPTC7_HUMAN:

Expressed in keratinocytes (at protein level).

Sequence:
MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD

Research Backgrounds

Function:

Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q. Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation.

Subcellular Location:

Mitochondrion matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in keratinocytes (at protein level).

Family&Domains:

Belongs to the PP2C family.

Restrictive clause

 

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