H1FNT Antibody - #DF15217

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Product: H1FNT Antibody
Catalog: DF15217
Description: Rabbit polyclonal antibody to H1FNT
Application: WB ELISA(peptide)
Reactivity: Human, Mouse
Mol.Wt.: 28kD(Calculated).
Uniprot: Q75WM6

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
H1FNT Antibody detects endogenous levels of H1FNT.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

H1 histone family member N testis specific; H1FNT; H1FNT_HUMAN; H1T2; HANP1; Haploid germ cell-specific nuclear protein 1; Histone H1t2; Testis-specific H1 histone;

Immunogens

Immunogen:

A synthesized peptide derived from human H1FNT.

Uniprot:

Q75WM6(H1FNT_HUMAN) >>Visit HPA database.

Gene(ID):
H1FNT(341567)
Expression:
Q75WM6 H1FNT_HUMAN:

Testis-specific.

Sequence:
MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQRTIQ

Research Backgrounds

Function:

Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1.

Subcellular Location:

Nucleus. Chromosome.
Note: In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Testis-specific.

Family&Domains:

Belongs to the histone H1/H5 family.

Restrictive clause

 

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