LCE3C Antibody - #DF15258

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Product: LCE3C Antibody
Catalog: DF15258
Description: Rabbit polyclonal antibody to LCE3C
Application: IHC IF/ICC
Reactivity: Human
Mol.Wt.: 10kD(Calculated).
Uniprot: Q5T5A8

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
LCE3C Antibody detects endogenous levels of LCE3C.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Late cornified envelope protein 3C; Late envelope protein 15; LCE3C; LEP15; Small proline rich like epidermal differentiation complex protein 3A; SPRL3A;

Immunogens

Immunogen:

A synthesized peptide derived from human LCE3C.

Uniprot:

Q5T5A8(LCE3C_HUMAN) >>Visit HPA database.

Gene(ID):
LCE3C(353144)
Expression:
Q5T5A8 LCE3C_HUMAN:

Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.

Sequence:
MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHFRSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC

Research Backgrounds

Function:

A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.

Tissue Specificity:

Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.

Family&Domains:

Belongs to the LCE family.

Restrictive clause

 

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