Product: MYCT1 Antibody
Catalog: DF15287
Description: Rabbit polyclonal antibody to MYCT1
Application: ELISA(peptide)
Reactivity: Human, Mouse
Mol.Wt.: 27kD(Calculated).
Uniprot: Q8N699

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
MYCT1 Antibody detects endogenous levels of MYCT1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1110020B04Rik; AI225941; AI642973; FLJ21269; MGC156309; MGC156310; MTLC; Mtmc1; Myc target 1; Myc target in myeloid cells protein 1; Myc target protein 1; Myct1; MYCT1_HUMAN;

Immunogens

Immunogen:

A synthesized peptide derived from human MYCT1.

Uniprot:
Gene(ID):
Expression:
Q8N699 MYCT1_HUMAN:

Down-regulated in gastric cancer tissues.

Sequence:
MRTQVYEGLCKNYFSLAVLQRDRIKLLFFDILVFLSVFLLFLLFLVDIMANNTTSLGSPWPENFWEDLIMSFTVSMAIGLVLGGFIWAVFICLSRRRRASAPISQWSSSRRSRSSYTHGLNRTGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRASTFHPFLQCPPLPVETESQLVTLPSSNISPTISTSHSLSRPDYWSSNSLRVGLSTPPPPAYESIIKAFPDS

Research Backgrounds

Function:

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).

Subcellular Location:

Nucleus.
Note: Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Down-regulated in gastric cancer tissues.

Family&Domains:

Belongs to the MYCT1 family.

Restrictive clause

 

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