TIMMDC1 Antibody - #DF15317

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Product: TIMMDC1 Antibody
Catalog: DF15317
Description: Rabbit polyclonal antibody to TIMMDC1
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 32kD(Calculated).
Uniprot: Q9NPL8

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TIMMDC1 Antibody detects endogenous levels of TIMMDC1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C3orf1; M5 14 protein; Protein M5-14; TIDC1_HUMAN; TIMMDC 1; timmdc1; Translocase of inner mitochondrial membrane domain containing 1; Translocase of inner mitochondrial membrane domain containing protein 1; Translocase of inner mitochondrial membrane domain-containing protein 1; Transmembrane protein C3orf1;

Immunogens

Immunogen:

A synthesized peptide derived from human TIMMDC1.

Uniprot:

Q9NPL8(TIDC1_HUMAN) >>Visit HPA database.

Gene(ID):
TIMMDC1(51300)
Expression:
Q9NPL8 TIDC1_HUMAN:

Generalized expression enhanced in heart and skeletal muscle.

Sequence:
MEVPPPAPRSFLCRALCLFPRVFAAEAVTADSEVLEERQKRLPYVPEPYYPESGWDRLRELFGKDEQQRISKDLANICKTAATAGIIGWVYGGIPAFIHAKQQYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWGWRTAVFVTIFNTVNTSLNVYRNKDALSHFVIAGAVTGSLFRINVGLRGLVAGGIIGALLGTPVGGLLMAFQKYSGETVQERKQKDRKALHELKLEEWKGRLQVTEHLPEKIESSLQEDEPENDAKKIEALLNLPRNPSVIDKQDKD

Research Backgrounds

Function:

Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.

Subcellular Location:

Mitochondrion membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Generalized expression enhanced in heart and skeletal muscle.

Subunit Structure:

Associates with the intermediate 315 kDa subcomplex of incompletely assembled complex I.

Family&Domains:

Belongs to the Tim17/Tim22/Tim23 family.

Restrictive clause

 

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