SNRPD2 Antibody - #DF15356
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
Sm-D2; small nuclear ribonucleoprotein D2; Small nuclear ribonucleoprotein D2 (RCG54604); small nuclear ribonucleoprotein D2 polypeptide (16.5kD); small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; SMALL NUCLEAR RIBONUCLEOPROTEIN POLYPEPTIDE D2; SNRPD2; Small nuclear ribonucleoprotein Sm D2; SMD2; SMD2_HUMAN; snRNP core protein D2; SNRPD1; Snrpd2; SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa;
Immunogens
A synthesized peptide derived from human SNRPD2.
- P62316 SMD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKSGKGKKKSKPVNKDRYISKMFLRGDSVIVVLRNPLIAGK
Research Backgrounds
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.
Cytoplasm>Cytosol. Nucleus.
Note: SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Belongs to the snRNP core protein family.
Research Fields
· Genetic Information Processing > Transcription > Spliceosome.
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