DEFA6 Antibody - #DF15380
(1)
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Protocols
Product Info
Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Polyclonal
Specificity:
DEFA6 Antibody detects endogenous levels of DEFA6.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
alpha 6; DEF6; DEF6_HUMAN; DEFA 6; DEFA6; Defensin 6; Defensin alpha 6; Defensin alpha 6 Paneth cell specific; Defensin; Defensin-6; HD 6; HD6;
Immunogens
Immunogen:
A synthesized peptide derived from human DEFA6.
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q01524 DEF6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL
Research Backgrounds
Function:
Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.
Subcellular Location:
Secreted.
Tissue Specificity:
Paneth cells of the small intestine.
Subunit Structure:
Homodimer.
Family&Domains:
Belongs to the alpha-defensin family.
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