EMC4 Antibody - #DF15412
(2)
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Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
EMC4 Antibody detects endogenous levels of EMC4.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Cell proliferation-inducing gene 17 protein; EMC4; ER membrane protein complex subunit 4; HSPC184; PIG17; tmem85; TMM85_HUMAN; Transmembrane protein 85;
Immunogens
Immunogen:
A synthesized peptide derived from human EMC4.
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q5J8M3 EMC4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTAQGGLVANRGRRFKWAIELSGPGGGSRGRSDRGSGQGDSLYPVGYLDKQVPDTSVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESSSQKFLQGLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEPPERMEFSGGGLLL
Research Backgrounds
Function:
May mediate anti-apoptotic activity.
Subcellular Location:
Membrane>Multi-pass membrane protein.
Tissue Specificity:
Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart.
Subunit Structure:
Component of the ER membrane protein complex (EMC).
Family&Domains:
Belongs to the EMC4 family.
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