Product: EDN2 Antibody
Catalog: DF15621
Description: Rabbit polyclonal antibody to EDN2
Application: IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 20kD(Calculated).
Uniprot: P20800

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
EDN2 Antibody detects endogenous levels of EDN2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EDN2; EDN2_HUMAN; Endothelin 2; Endothelin-2; ET 2; ET-2; ET2; PPET2; Preproendothelin 2; Preproendothelin-2;

Immunogens

Immunogen:

A synthesized peptide derived from human EDN2.

Uniprot:
Gene(ID):
Expression:
P20800 EDN2_HUMAN:

Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells.

Sequence:
MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR

Research Backgrounds

Function:

Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells.

Family&Domains:

Belongs to the endothelin/sarafotoxin family.

Restrictive clause

 

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