Product: HILPDA Antibody
Catalog: DF15774
Description: Rabbit polyclonal antibody to HILPDA
Application: IHC
Reactivity: Human
Mol.Wt.: 7kD(Calculated).
Uniprot: Q9Y5L2

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
HILPDA Antibody detects endogenous levels of HILPDA.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C7orf68; chromosome 7 open reading frame 68; HIG 2; HIG2; HIG2_HUMAN; HILPDA; hypoxia inducible gene 2; Hypoxia-inducible gene 2 protein; Hypoxia-inducible lipid droplet-associated protein; Hypoxia-inducible protein 2;

Immunogens

Immunogen:

A synthesized peptide derived from human HILPDA.

Uniprot:
Gene(ID):
Expression:
Q9Y5L2 HLPDA_HUMAN:

Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level).

Sequence:
MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM

Research Backgrounds

Function:

Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation.

Subcellular Location:

Lipid droplet. Secreted. Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level).

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