TRAT1 Antibody - #DF15785

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Product: TRAT1 Antibody
Catalog: DF15785
Description: Rabbit polyclonal antibody to TRAT1
Application: IHC
Reactivity: Human
Mol.Wt.: 21kD(Calculated).
Uniprot: Q6PIZ9

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
TRAT1 Antibody detects endogenous levels of TRAT1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HSPC062; pp29/30; T cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; TRAT1; TRAT1_HUMAN; TRIM;

Immunogens

Immunogen:

A synthesized peptide derived from human TRAT1.

Uniprot:

Q6PIZ9(TRAT1_HUMAN) >>Visit HPA database.

Gene(ID):
TRAT1(50852)
Expression:
Q6PIZ9 TRAT1_HUMAN:

Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).

Sequence:
MSGISGCPFFLWGLLALLGLALVISLIFNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDENCYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQNTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN

Research Backgrounds

Function:

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

PTMs:

Phosphorylated on tyrosines by LCK or FYN upon TCR activation.

Subcellular Location:

Cell membrane>Single-pass type III membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).

Subunit Structure:

Homodimer; disulfide-linked. Interacts with CD3Z. When phosphorylated, interacts with PIK3R1.

Restrictive clause

 

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For Research Use Only.
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