ABI3 Antibody - #DF15821

(3)  
Product: ABI3 Antibody
Catalog: DF15821
Description: Rabbit polyclonal antibody to ABI3
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 39kD(Calculated).
Uniprot: Q9P2A4

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
ABI3 Antibody detects endogenous levels of ABI3.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ABI family member 3; ABI gene family member 3; Nesh; New molecule including SH3; SSH3BP3;

Immunogens

Immunogen:

A synthesized peptide derived from human ABI3.

Uniprot:

Q9P2A4(ABI3_HUMAN) >>Visit HPA database.

Gene(ID):
ABI3(51225)
Expression:
Q9P2A4 ABI3_HUMAN:

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.

Sequence:
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC

Research Backgrounds

Function:

May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.

Subcellular Location:

Cytoplasm.
Note: Colocalizes with PAK2 at leading edge of cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.

Subunit Structure:

May interact with PAK1 and PAK2. Probably interacts with TARSH.

Family&Domains:

Belongs to the ABI family.

Restrictive clause

 

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