PLGRKT Antibody - #DF15855

(2)  
Product: PLGRKT Antibody
Catalog: DF15855
Description: Rabbit polyclonal antibody to PLGRKT
Application: IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 17kD(Calculated).
Uniprot: Q9HBL7

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
PLGRKT Antibody detects endogenous levels of PLGRKT.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AD025; Chromosome 9 open reading frame 46; FLJ14688; FLJ39176; Hypothetical protein LOC55848; MDS030; transmembrane protein C9orf46; Uncharacterized hematopoietic stem/progenitor cells protein MDS030;

Immunogens

Immunogen:

A synthesized peptide derived from human PLGRKT.

Uniprot:

Q9HBL7(PLRKT_HUMAN) >>Visit HPA database.

Gene(ID):
PLGRKT(55848)
Expression:
Q9HBL7 PLRKT_HUMAN:

Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla.

Sequence:
MGFIFSKSMNESMKNQKEFMLMNARLQLERQLIMQSEMRERQMAMQIAWSREFLKYFGTFFGLAAISLTAGAIKKKKPAFLVPIVPLSFILTYQYDLGYGTLLERMKGEAEDILETEKSKLQLPRGMITFESIEKARKEQSRFFIDK

Research Backgrounds

Function:

Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.
Note: Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla.

Subunit Structure:

Interacts with PLAT and PLAUR.

Restrictive clause

 

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