TREX2 Antibody - #DF15876

Product: TREX2 Antibody
Catalog: DF15876
Description: Rabbit polyclonal antibody to TREX2
Application: ELISA(peptide)
Reactivity: Human
Mol.Wt.: 26kD(Calculated).
Uniprot: Q9BQ50

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
TREX2 Antibody detects endogenous levels of TREX2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

3' 5' exonuclease; 3' 5' exonuclease TREX2; 3'-5' exonuclease TREX2; Three prime repair exonuclease 2; TREX 2; TREX2; TREX2_HUMAN;

Immunogens

Immunogen:

A synthesized peptide derived from human TREX2.

Uniprot:

Q9BQ50(TREX2_HUMAN) >>Visit HPA database.

Gene(ID):
TREX2(11219)
Expression:
Q9BQ50 TREX2_HUMAN:

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.

Sequence:
MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGFDYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA

Research Backgrounds

Function:

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the exonuclease superfamily. TREX family.

Restrictive clause

 

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