METTL21A Antibody - #DF15919

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Product: METTL21A Antibody
Catalog: DF15919
Description: Rabbit polyclonal antibody to METTL21A
Application: IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 25kD(Calculated).
Uniprot: Q8WXB1

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
METTL21A Antibody detects endogenous levels of METTL21A.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

F119A_HUMAN; FAM119A; Family with sequence similarity 119 member A; HCA557b; Hepatocellular carcinoma-associated antigen 557b; Hypothetical protein LOC151194; LOC151194; Methyltransferase like 21A; Methyltransferase like protein 21A; METTL21A; MGC45373; Protein FAM119A;

Immunogens

Immunogen:

A synthesized peptide derived from human METTL21A.

Uniprot:

Q8WXB1(MT21A_HUMAN) >>Visit HPA database.

Gene(ID):
METTL21A(151194)
Sequence:
MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDWRHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYERDNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL

Research Backgrounds

Function:

Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with heat shock protein 70 family members; at least some of these proteins are methylation substratesand.

Family&Domains:

Belongs to the methyltransferase superfamily. METTL21 family.

Restrictive clause

 

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