CRELD2 Antibody - #DF16071

(2)  
Product: CRELD2 Antibody
Catalog: DF16071
Description: Rabbit polyclonal antibody to CRELD2
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 38kD(Calculated).
Uniprot: Q6UXH1

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
CRELD2 Antibody detects endogenous levels of CRELD2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CREL2_HUMAN; CRELD 2; CRELD2; Cysteine rich with EGF like domain protein 2; Cysteine rich with EGF like domains 2; Cysteine-rich with EGF-like domain protein 2; DKFZp667O055; MGC11256;

Immunogens

Immunogen:

A synthesized peptide derived from human CRELD2.

Uniprot:

Q6UXH1(CREL2_HUMAN) >>Visit HPA database.

Gene(ID):
CRELD2(79174)
Expression:
Q6UXH1 CREL2_HUMAN:

Ubiquitously expressed (PubMed:16238698). Highly expressed in skeletal muscle, heart, liver, kidney and placenta (PubMed:16238698).

Sequence:
MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL

Research Backgrounds

Function:

Protein disulfide isomerase (By similarity). Might play a role in the unfolded protein response (By similarity). May regulate transport of alpha4-beta2 neuronal acetylcholine receptor.

Subcellular Location:

Endoplasmic reticulum.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitously expressed. Highly expressed in skeletal muscle, heart, liver, kidney and placenta.

Subunit Structure:

Interacts with CHRNA4. Component of a complex containing at least CRELD2, MANF, MATN3 and PDIA4 (By similarity).

Family&Domains:

Belongs to the CRELD family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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