DDX3Y Antibody - #DF16083
Product: | DDX3Y Antibody |
Catalog: | DF16083 |
Description: | Rabbit polyclonal antibody to DDX3Y |
Application: | ELISA(peptide) |
Reactivity: | Human, Mouse |
Mol.Wt.: | 85kD; 73kD(Calculated). |
Uniprot: | O15523 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
ATP dependent RNA helicase DDX3Y; ATP-dependent RNA helicase DDX3Y; DBY; DDX3Y; DDX3Y_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y linked; DEAD box protein 3 Y chromosomal; DEAD box protein 3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide Y chromosome; Y-chromosomal;
Immunogens
A synthesized peptide derived from human DDX3Y.
Widely expressed at the mRNA level, with highest levels in testis (PubMed:9381176). Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes (PubMed:15294876).
- O15523 DDX3Y_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGWSCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Research Backgrounds
Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity).
Cytoplasm. Nucleus.
Note: Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.
Widely expressed at the mRNA level, with highest levels in testis. Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes.
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
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