ARL14 Antibody - #DF16123

(3)  
Product: ARL14 Antibody
Catalog: DF16123
Description: Rabbit polyclonal antibody to ARL14
Application: WB IHC IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 22kD(Calculated).
Uniprot: Q8N4G2

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
ARL14 Antibody detects endogenous levels of ARL14.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ADP ribosylation factor like 14; ADP-ribosylation factor 7; ADP-ribosylation factor-like protein 14; ARF7; ARL14; ARL14_HUMAN; FLJ22595; OTTHUMP00000213879;

Immunogens

Immunogen:

A synthesized peptide derived from human ARL14.

Uniprot:

Q8N4G2(ARL14_HUMAN) >>Visit HPA database.

Gene(ID):
ARL14(80117)
Expression:
Q8N4G2 ARL14_HUMAN:

Expressed in immature dendritic cells.

Sequence:
MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN

Research Backgrounds

Function:

GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.

Subcellular Location:

Cytoplasmic vesicle.
Note: Colocalizes with MHC II-containing cytoplasmic vesicles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in immature dendritic cells.

Subunit Structure:

Interacts with ARL14EP.

Family&Domains:

Belongs to the small GTPase superfamily. Arf family.

Restrictive clause

 

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