AFfirm™ MZF-1 Mouse Monoclonal Antibody - #BF9307
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
Myeloid zinc finger 1; MZF 1; MZF-1; MZF1; MZF1_HUMAN; MZF1B; Zfp98; Zinc finger and SCAN domain containing protein 6; Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42; ZNF42; ZSCAN6;
Immunogens
Preferentially expressed in differentiating myeloid cells. Detected in osteoblasts.
- P28698 MZF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRPAVLGSPDRAPPEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWLRPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWVTVQVQGQEVLSEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTEDSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGPSWREHPRALWHEEAGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREGGFAHALLLPSDLRSEQDPTDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE
PTMs - P28698 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S8 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| S111 | Phosphorylation | Uniprot | |
| T134 | Phosphorylation | Uniprot | |
| T169 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Q16539 (MAPK14) , P27361 (MAPK3) | Uniprot |
| S274 | Phosphorylation | Q16539 (MAPK14) , P27361 (MAPK3) | Uniprot |
| S294 | Phosphorylation | Q16539 (MAPK14) , P27361 (MAPK3) | Uniprot |
| S347 | Phosphorylation | Uniprot | |
| T592 | Phosphorylation | Uniprot | |
| K595 | Sumoylation | Uniprot | |
| T618 | Phosphorylation | Uniprot | |
| T620 | Phosphorylation | Uniprot | |
| K723 | Sumoylation | Uniprot |
Research Backgrounds
Binds to target promoter DNA and functions as transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.
Nucleus.
Preferentially expressed in differentiating myeloid cells. Detected in osteoblasts.
Homodimer.
Belongs to the krueppel C2H2-type zinc-finger protein family.
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