AFfirm™ CARKL Mouse Monoclonal Antibody - #BF9360

Product: CARKL Mouse Monoclonal Antibody
Catalog: BF9360
Description: Mouse monoclonal antibody to CARKL
Application: WB
Reactivity: Human
Prediction: Mouse, Rat, Pig, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 55 KD; 51kD(Calculated).
Uniprot: Q9UHJ6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm9360]
Specificity:
CARKL Mouse Monoclonal Antibody detects endogenous levels of total CARKL.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Carbohydrate kinase like; Carbohydrate kinase like protein; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk; SHPK_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q9UHJ6(SHPK_HUMAN) >>Visit HPA database.

Gene(ID):
SHPK(23729)
Expression:
Q9UHJ6 SHPK_HUMAN:

Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.

Sequence:
MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQDWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES

PTMs - Q9UHJ6 As Substrate

Site PTM Type Enzyme
S30 Phosphorylation
S37 Phosphorylation
R426 Methylation
K441 Ubiquitination

Research Backgrounds

Function:

Acts as a modulator of macrophage activation through control of glucose metabolism.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.

Family&Domains:

Belongs to the FGGY kinase family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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