AFfirm™ SLC24A3 Mouse Monoclonal Antibody - #BF9451

Product: SLC24A3 Mouse Monoclonal Antibody
Catalog: BF9451
Description: Mouse monoclonal antibody to SLC24A3
Application: WB
Reactivity: Human
Prediction: Mouse, Rat, Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 61 KD; 72kD(Calculated).
Uniprot: Q9HC58

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm9451]
Specificity:
SLC24A3 Mouse Monoclonal Antibody detects endogenous levels of total SLC24A3.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Na(+)/K(+)/Ca(2+)-exchange protein 3; NCKX3; NCKX3_HUMAN; RP1-122P22.1; Slc24a3; Sodium calcium exchanger; Sodium/potassium/calcium exchanger 3; Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3; Solute carrier family 24 member 3;

Immunogens

Immunogen:
Uniprot:

Q9HC58(NCKX3_HUMAN) >>Visit HPA database.

Gene(ID):
SLC24A3(57419)
Expression:
Q9HC58 NCKX3_HUMAN:

Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.

Sequence:
MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH

PTMs - Q9HC58 As Substrate

Site PTM Type Enzyme
S42 Phosphorylation
Y248 Phosphorylation
Y251 Phosphorylation
S308 Phosphorylation
S345 Phosphorylation

Research Backgrounds

Function:

Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.

Family&Domains:

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.

Restrictive clause

 

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