AFfirm™ FGF13 Mouse Monoclonal Antibody - #BF9598
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Protocols
Product Info
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
FGF 13; FGF 2; FGF-13; FGF13; FGF13_HUMAN; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; OTTHUMP00000024144;
Immunogens
A synthesized peptide derived from human FGF13, corresponding to a region within the internal amino acids.
- Q92913 FGF13_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
Research Backgrounds
Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity).
May be phosphorylated.
Cell projection>Filopodium. Cell projection>Growth cone. Cell projection>Dendrite. Nucleus. Cytoplasm.
Note: Not secreted.
Nucleus>Nucleolus.
Cytoplasm. Nucleus.
Ubiquitously expressed. Predominantly expressed in the nervous system.
Belongs to the heparin-binding growth factors family.
Restrictive clause
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For Research Use Only.
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