LAT3 Antibody - #DF3041
| Product: | LAT3 Antibody |
| Catalog: | DF3041 |
| Description: | Rabbit polyclonal antibody to LAT3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Sheep |
| Mol.Wt.: | 61 KD; 61kD(Calculated). |
| Uniprot: | O75387 |
| RRID: | AB_2835424 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3041, RRID:AB_2835424.
Fold/Unfold
L type amino acid transporter 3; L-type amino acid transporter 3; Large neutral amino acids transporter small subunit 3; LAT3_HUMAN; PB39; POV1; Prostate cancer overexpressed gene 1 protein; R00504; SLC43A1; Solute carrier family 43 member 1;
Immunogens
In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.
- O75387 LAT3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGPLKVLSGSEVTA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75387 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y46 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| T246 | Phosphorylation | Uniprot | |
| Y251 | Phosphorylation | Uniprot | |
| T256 | Phosphorylation | Uniprot | |
| S262 | Phosphorylation | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Uniprot | |
| S285 | Phosphorylation | Uniprot | |
| S298 | Phosphorylation | Uniprot | |
| Y321 | Phosphorylation | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| K404 | Ubiquitination | Uniprot | |
| T426 | Phosphorylation | Uniprot | |
| T558 | Phosphorylation | Uniprot |
Research Backgrounds
Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
Membrane>Multi-pass membrane protein.
In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
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