Product: ZNF24 Antibody
Catalog: DF3101
Description: Rabbit polyclonal antibody to ZNF24
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Horse, Sheep, Dog
Mol.Wt.: 48 KD; 42kD(Calculated).
Uniprot: P17028
RRID: AB_2835478

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Horse(100%), Sheep(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
ZNF24 Antibody detects endogenous levels of total ZNF24.
RRID:
AB_2835478
Cite Format: Affinity Biosciences Cat# DF3101, RRID:AB_2835478.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

KOX17; Retinoic acid suppression protein A; RSG A; RSG-A; RSGA; Zfp191; Zinc finger and SCAN domain containing protein 3; Zinc finger and SCAN domain-containing protein 3; Zinc finger protein 191; Zinc finger protein 24; Zinc finger protein KOX17; ZNF 24; ZNF191; ZNF24; ZNF24_HUMAN; ZSCAN 3; ZSCAN3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P17028 ZNF24_HUMAN:

Expressed in many tissues except in heart.

Sequence:
MSAQSVEEDSILIIPTPDEEEKILRVKLEEDPDGEEGSSIPWNHLPDPEIFRQRFRQFGYQDSPGPREAVSQLRELCRLWLRPETHTKEQILELVVLEQFVAILPKELQTWVRDHHPENGEEAVTVLEDLESELDDPGQPVSLRRRKREVLVEDMVSQEEAQGLPSSELDAVENQLKWASWELHSLRHCDDDGRTENGALAPKQELPSALESHEVPGTLNMGVPQIFKYGETCFPKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEKLLNVVKV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
100
Dog
100
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P17028 As Substrate

Site PTM Type Enzyme
T16 Phosphorylation
K27 Sumoylation
K27 Ubiquitination
R56 Methylation
S63 Phosphorylation
S132 Phosphorylation
S142 Phosphorylation
S157 Phosphorylation
S166 Phosphorylation
S180 Phosphorylation
S185 Phosphorylation
T195 Phosphorylation
K236 Sumoylation
K236 Ubiquitination
S261 Phosphorylation
R271 Methylation
S274 Phosphorylation
K277 Sumoylation
Y279 Phosphorylation
K286 Sumoylation
K286 Ubiquitination
S292 Phosphorylation
T302 Phosphorylation
K305 Sumoylation
K305 Ubiquitination
K308 Sumoylation
K314 Sumoylation
T330 Phosphorylation
K333 Sumoylation
K333 Ubiquitination
Y335 Phosphorylation
K342 Sumoylation
K361 Methylation
K361 Sumoylation
K367 Sumoylation
K367 Ubiquitination

Research Backgrounds

Function:

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.

PTMs:

Sumoylated.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in many tissues except in heart.

Family&Domains:

Belongs to the krueppel C2H2-type zinc-finger protein family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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