Product: PTX3 Antibody
Catalog: DF3132
Description: Rabbit polyclonal antibody to PTX3
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Bovine, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 40 KD; 42kD(Calculated).
Uniprot: P26022
RRID: AB_2835509

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(100%), Sheep(91%), Rabbit(91%), Dog(82%), Chicken(88%)
Clonality:
Polyclonal
Specificity:
PTX3 Antibody detects endogenous levels of total PTX3.
RRID:
AB_2835509
Cite Format: Affinity Biosciences Cat# DF3132, RRID:AB_2835509.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AI607804; Pentaxin 3; Pentaxin-related protein PTX3; Pentraxin 3 long; Pentraxin-related gene; Pentraxin-related gene rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3_HUMAN; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
91
Rabbit
91
Chicken
88
Dog
82
Xenopus
55
Pig
0
Horse
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P26022 As Substrate

Site PTM Type Enzyme
T159 Phosphorylation
T222 Phosphorylation

Research Backgrounds

Function:

Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.

PTMs:

Glycosylated.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homooctamer; disulfide-linked. Binds to C1q (By similarity).

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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