HIPK4 Antibody - #DF3352
| Product: | HIPK4 Antibody |
| Catalog: | DF3352 |
| Description: | Rabbit polyclonal antibody to HIPK4 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Rabbit |
| Mol.Wt.: | 70 KD; 69kD(Calculated). |
| Uniprot: | Q8NE63 |
| RRID: | AB_2835568 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3352, RRID:AB_2835568.
Fold/Unfold
HIPK 4; HIPK4; HIPK4_HUMAN; Homeodomain interacting protein kinase 4; Homeodomain-interacting protein kinase 4;
Immunogens
- Q8NE63 HIPK4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAPGMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSSRLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQRDEDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQHGPPRGATSFLQHVTGHH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NE63 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K19 | Acetylation | Uniprot | |
| K27 | Acetylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| T122 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| S337 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| T381 | Phosphorylation | Uniprot | |
| T390 | Phosphorylation | Uniprot | |
| Y392 | Phosphorylation | Uniprot | |
| Y393 | Phosphorylation | Uniprot |
Research Backgrounds
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential).
Autophosphorylated.
Cytoplasm.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
Research Fields
· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)
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