CD163 Recombinant Rabbit mAb - #BF4121
Out of stock
Control Products
Product Info
Source:
Rabbit IgG
Application:
WB 1:1000, IHC 1:200-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human, Mouse, Rat
Clonality:
Monoclonal [ReFirm23568]
Specificity:
CD163 Recombinant Rabbit mAb detects endogenous levels of CD163.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
CD163v2,CD163v3
Immunogens
Immunogen:
A synthetic peptide from mouse CD163
Description:
Involved in clearance and endocytosis of hemoglobin,haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron,via endocytosis of hemoglobin,haptoglobin and subsequent breakdown of heme. Binds hemoglobin,haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization,inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
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For Research Use Only.
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