Product: IL-33 Recombinant Rabbit mAb
Catalog: BF4142
Description: Rabbit monoclonal antibody to IL-33
Application: WB IHC IF/ICC
Reactivity: Mouse, Rat
Mol.Wt.: 30 kDa(Observed);
Uniprot: Q8BVZ5

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Product Info

Source:
Rabbit IgG
Application:
WB 1:1000, IHC 1:200-1:2000, ICC
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Mouse, Rat
Clonality:
Monoclonal [ReFirm23589]
Specificity:
IL-33 Recombinant Rabbit mAb detects endogenous levels of IL-33.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Il-33,Il1f11,NF-HEV,9230117N10Rik

Immunogens

Immunogen:

A synthetic peptide from mouse IL-33

Description:
Cytokine that binds to and signals through the IL1RL1,ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells,basophils,eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells,and may function as an "alarmin",that amplifies immune responses during tissue injury.

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