APOA2 Recombinant Rabbit mAb - #BF4280

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Product: APOA2 Recombinant Rabbit mAb
Catalog: BF4280
Description: Rabbit monoclonal antibody to APOA2
Application: WB IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 11 kDa(Observed); 11kD(Calculated).
Uniprot: P02652

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit IgG
Application:
WB 1:1000-1:5000, ICC
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human, Rat
Clonality:
Monoclonal [ReFirm23730]
Specificity:
APOA2 Recombinant Rabbit mAb detects endogenous levels of APOA2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

APO A2; Apo AII; Apo-AII; APOA 2; ApoA II; ApoA-II; APOA2; APOA2_HUMAN; APOAII; Apolipoprotein A II; Apolipoprotein A-II(1-76); Apolipoprotein A2; Apolipoprotein AII; ApolipoproteinA II; OTTHUMP00000032244;

Immunogens

Immunogen:

A synthetic peptide from human APOA2

Uniprot:

P02652(APOA2_HUMAN) >>Visit HPA database.

Gene(ID):
APOA2(336)
Expression:
P02652 APOA2_HUMAN:

Plasma; synthesized in the liver and intestine.

Description:
This gene encodes apolipoprotein (apo-) A-II,which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer,homodimer,or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
Sequence:
MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ

Research Backgrounds

Function:

May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.

PTMs:

Phosphorylation sites are present in the extracellular medium.

Apolipoprotein A-II is O-glycosylated.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Plasma; synthesized in the liver and intestine.

Family&Domains:

Belongs to the apolipoprotein A2 family.

Research Fields

· Organismal Systems > Endocrine system > PPAR signaling pathway.

· Organismal Systems > Digestive system > Cholesterol metabolism.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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