FAKD3 Antibody - #DF3281
| Product: | FAKD3 Antibody |
| Catalog: | DF3281 |
| Description: | Rabbit polyclonal antibody to FAKD3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Sheep |
| Mol.Wt.: | 75 KD; 76kD(Calculated). |
| Uniprot: | Q14CZ7 |
| RRID: | AB_2835649 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3281, RRID:AB_2835649.
Fold/Unfold
FAKD3_HUMAN; FAST kinase domain containing protein 3; FAST kinase domain-containing protein 3; FAST kinase domains 3; Fastkd3; FLJ23274; MGC142123; MGC5297;
Immunogens
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
- Q14CZ7 FAKD3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVKFHHAHCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFISTMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWLQE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14CZ7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T252 | Phosphorylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| T330 | Phosphorylation | Uniprot | |
| S483 | Phosphorylation | Uniprot | |
| K519 | Ubiquitination | Uniprot | |
| K589 | Ubiquitination | Uniprot | |
| K611 | Ubiquitination | Uniprot | |
| Y624 | Phosphorylation | Uniprot |
Research Backgrounds
Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.
Mitochondrion.
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
RAP domain is required for FASTKD3 function in mRNA stability and translation.
Belongs to the FAST kinase family.
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