TSN Antibody - #DF3292
| Product: | TSN Antibody |
| Catalog: | DF3292 |
| Description: | Rabbit polyclonal antibody to TSN |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 26 KD; 26kD(Calculated). |
| Uniprot: | Q15631 |
| RRID: | AB_2835660 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3292, RRID:AB_2835660.
Fold/Unfold
BCLF 1; BCLF1; Component 3 of promoter of RISC; RCHF1; recombination hotspot associated factor; recombination hotspot binding protein; rehf 1; REHF1; TBRBP; Translin; TRSLN; TSN; TSN_HUMAN;
Immunogens
- Q15631 TSN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACVEK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15631 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T34 | Phosphorylation | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| T70 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K187 | Acetylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| K199 | Acetylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| R215 | Methylation | Uniprot | |
| K219 | Ubiquitination | Uniprot | |
| C225 | S-Nitrosylation | Uniprot | |
| K228 | Acetylation | Uniprot |
Research Backgrounds
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
Cytoplasm. Nucleus.
Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.
Belongs to the translin family.
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