TSSC1 Antibody - #DF3314
| Product: | TSSC1 Antibody |
| Catalog: | DF3314 |
| Description: | Rabbit polyclonal antibody to TSSC1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Chicken |
| Mol.Wt.: | 48 KD; 44kD(Calculated). |
| Uniprot: | Q53HC9 |
| RRID: | AB_2835682 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3314, RRID:AB_2835682.
Fold/Unfold
TSSC 1; Tumor suppressing STF cDNA 1 protein; Tumor suppressing subchromosomal transferable fragment; Tumor suppressing subchromosomal transferable fragment candidate gene 1 protein; Tumor suppressing subtransferable candidate 1;
Immunogens
- Q53HC9 EIPR1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRTSDSKVLTCAAVWRMPKELESGSHESPDDSSSTAQTLELLCHLDNTAHGNMACVVWEPMGDGKKIISLADNHILLWDLQESSSQAVLASSASLEGKGQLKFTSGRWSPHHNCTQVATANDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q53HC9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| T94 | Phosphorylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| Y242 | Phosphorylation | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| Y280 | Phosphorylation | Uniprot | |
| T290 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| S306 | Phosphorylation | Uniprot | |
| S320 | Phosphorylation | Uniprot | |
| K382 | Ubiquitination | Uniprot |
Research Backgrounds
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex.
Golgi apparatus>trans-Golgi network.
Interacts with two multisubunit tethering complexes: EARP composed of VPS50, VPS51, VPS52 and VPS53 subunits and GARP complex composed of VPS51, VPS52, VPS53 and VPS54 subunits. Interacts with SNAP29.
Belongs to the WD repeat EIPR1 family.
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