AZI2 Antibody - #DF3437
| Product: | AZI2 Antibody |
| Catalog: | DF3437 |
| Description: | Rabbit polyclonal antibody to AZI2 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig |
| Mol.Wt.: | 48 KD; 45kD(Calculated). |
| Uniprot: | Q9H6S1 |
| RRID: | AB_2835737 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3437, RRID:AB_2835737.
Fold/Unfold
5 azacytidine induced protein 2; 5-azacytidine-induced protein 2; AA410145; AZ2; AZI2; AZI2_HUMAN; MGC112644; Nak associated protein 1; Nak-associated protein 1; NAP1; NF kappa B activating kinase associated protein 1; NF-kappa-B-activating kinase-associated protein 1; TILP; TILP(S);
Immunogens
A synthesized peptide derived from human AZI2, corresponding to a region within N-terminal amino acids.
- Q9H6S1 AZI2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTSSPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSETAFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
Cytoplasm.
Widely expressed. Abundant expression seen in the pancreas and testis.
Research Fields
· Organismal Systems > Immune system > RIG-I-like receptor signaling pathway. (View pathway)
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