GTF3C2 Antibody - #DF3372

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Product: GTF3C2 Antibody
Catalog: DF3372
Description: Rabbit polyclonal antibody to GTF3C2
Application: WB IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 100 KD; 101kD(Calculated).
Uniprot: Q8WUA4
RRID: AB_2835754

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(82%), Bovine(92%), Horse(100%), Sheep(92%), Rabbit(92%), Dog(92%)
Clonality:
Polyclonal
Specificity:
GTF3C2 Antibody detects endogenous levels of total GTF3C2.
RRID:
AB_2835754
Cite Format: Affinity Biosciences Cat# DF3372, RRID:AB_2835754.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

General transcription factor 3C polypeptide 2; General transcription factor IIIC polypeptide 2 beta 110kDa; Gtf3c2; KIAA0011; TF3C beta; TF3C-beta; TF3C2_HUMAN; TFIIIC 110 kDa subunit; TFIIIC BETA; TFIIIC110; Transcription factor IIIC 110 kDa subunit; Transcription factor IIIC subunit beta;

Immunogens

Immunogen:
Uniprot:

Q8WUA4(TF3C2_HUMAN) >>Visit HPA database.

Gene(ID):
GTF3C2(2976)
Sequence:
MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSHRLLPTP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
92
Sheep
92
Dog
92
Rabbit
92
Pig
82
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8WUA4 As Substrate

Site PTM Type Enzyme
S25 Phosphorylation
S39 Phosphorylation
S48 Phosphorylation
S63 Phosphorylation
S85 Phosphorylation
S132 Phosphorylation
S136 Phosphorylation
T137 Phosphorylation
S147 Phosphorylation
K148 Methylation
K155 Ubiquitination
S157 Phosphorylation
S165 Phosphorylation
S167 Phosphorylation
T177 Phosphorylation
S220 Phosphorylation
S260 Phosphorylation
S264 Phosphorylation
S268 Phosphorylation
K315 Ubiquitination
K354 Ubiquitination
S379 Phosphorylation
T486 Phosphorylation
K489 Ubiquitination
S504 Phosphorylation
S597 Phosphorylation
K602 Ubiquitination
K623 Methylation
K639 Ubiquitination
Y647 Phosphorylation
K756 Ubiquitination
S765 Phosphorylation
K783 Ubiquitination
R831 Methylation
K839 Ubiquitination
S871 Phosphorylation
R876 Methylation
S892 Phosphorylation
S893 Phosphorylation
T895 Phosphorylation
S901 Phosphorylation
T903 Phosphorylation
S904 Phosphorylation
T910 Phosphorylation

Research Backgrounds

Function:

Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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