ORAOV1 Antibody - #DF3373

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Product: ORAOV1 Antibody
Catalog: DF3373
Description: Rabbit polyclonal antibody to ORAOV1
Application: WB IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 15 KD; 15kD(Calculated).
Uniprot: Q8WV07
RRID: AB_2835755

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
ORAOV1 Antibody detects endogenous levels of total ORAOV1.
RRID:
AB_2835755
Cite Format: Affinity Biosciences Cat# DF3373, RRID:AB_2835755.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Oral cancer overexpressed 1; Oral cancer overexpressed protein 1 A; Oral cancer-overexpressed protein 1; ORAOV1; ORAOV1 oral cancer overexpressed 1; ORAV1_HUMAN; TAOS1; Tumor amplified and overexpressed sequence 1; Tumor-amplified and overexpressed sequence 1;

Immunogens

Immunogen:
Uniprot:

Q8WV07(LTO1_HUMAN) >>Visit HPA database.

Gene(ID):
ORAOV1(220064)
Expression:
Q8WV07 LTO1_HUMAN:

Widely expressed. Highly expressed in placenta, kidney and skeletal muscle.

Sequence:
MAGSQDIFDAIVMADERFHGEGYREGYEEGSSLGVMEGRQHGTLHGAKIGSEIGCYQGFAFAWKCLLHSCTTEKDSRKMKVLESLIGMIQKFPYDDPTYDKLHEDLDKIRGKFKQFCSLLNVQPDFKISAEGSGLSF

PTMs - Q8WV07 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S4 Phosphorylation
Y23 Phosphorylation
K114 Acetylation
S136 Phosphorylation

Research Backgrounds

Function:

The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation. May play a role in the regulation of proline metabolism and ROS production.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Highly expressed in placenta, kidney and skeletal muscle.

Subunit Structure:

Forms a complex with YAE1. Interacts with PYCR1 and PYCR2.

Family&Domains:

Belongs to the LTO1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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