ADD3 Antibody - #DF3510
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3510, RRID:AB_2835872.
Fold/Unfold
ADD3; ADDG_HUMAN; ADDL; Adducin 3 (gamma); Adducin 3; Adducin, gamma; Adducin-like; Adducin-like protein 70; Gamma-adducin;
Immunogens
- Q9UEY8 ADDG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UEY8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| T12 | Phosphorylation | Uniprot | |
| S17 | Phosphorylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| R27 | Methylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| T59 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| K280 | Ubiquitination | Uniprot | |
| K340 | Methylation | Uniprot | |
| S360 | Phosphorylation | Uniprot | |
| Y383 | Phosphorylation | Uniprot | |
| Y389 | Phosphorylation | Uniprot | |
| R390 | Methylation | Uniprot | |
| S402 | Phosphorylation | Uniprot | |
| T409 | Phosphorylation | Uniprot | |
| T411 | Phosphorylation | Uniprot | |
| S414 | Phosphorylation | Uniprot | |
| T419 | Phosphorylation | Uniprot | |
| S423 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K426 | Ubiquitination | Uniprot | |
| Y427 | Phosphorylation | Uniprot | |
| K436 | Acetylation | Uniprot | |
| S442 | Phosphorylation | Uniprot | |
| T445 | Phosphorylation | Uniprot | |
| Y446 | Phosphorylation | Uniprot | |
| K448 | Ubiquitination | Uniprot | |
| S455 | Phosphorylation | Uniprot | |
| T460 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| T464 | Phosphorylation | Uniprot | |
| T467 | Phosphorylation | Uniprot | |
| S478 | Phosphorylation | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| K504 | Ubiquitination | Uniprot | |
| Y565 | Phosphorylation | Uniprot | |
| S618 | Phosphorylation | Uniprot | |
| S621 | Phosphorylation | Uniprot | |
| S647 | Phosphorylation | Uniprot | |
| S650 | Phosphorylation | Uniprot | |
| T651 | Phosphorylation | Uniprot | |
| S652 | Phosphorylation | Uniprot | |
| T654 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S677 | Phosphorylation | Uniprot | |
| S679 | Phosphorylation | Uniprot | |
| S681 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| T691 | Phosphorylation | Uniprot | |
| S693 | Phosphorylation | O14757 (CHEK1) | Uniprot |
Research Backgrounds
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Plays a role in actin filament capping. Binds to calmodulin.
Sumoylated.
Cytoplasm>Cytoskeleton. Cell membrane>Peripheral membrane protein>Cytoplasmic side.
Isoform 1 is ubiquitously expressed.
Heterodimer of an alpha and a gamma subunit.
Comprised of three regions: a N-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.
Belongs to the aldolase class II family. Adducin subfamily.
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