ELOA3 Antibody - #DF3614
| Product: | ELOA3 Antibody |
| Catalog: | DF3614 |
| Description: | Rabbit polyclonal antibody to ELOA3 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 60 KD; 60kD(Calculated). |
| Uniprot: | Q8NG57 |
| RRID: | AB_2835986 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3614, RRID:AB_2835986.
Fold/Unfold
EloA3; Elongin A3; HsT829; RNA polymerase II transcription factor SIII subunit A3; TCEB3L2; Transcription elongation factor B polypeptide 3C; transcription elongation factor B polypeptide 3C (elongin A3);
Immunogens
- Q8NG57 ELOA3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQHVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQANYDLLSAFEAMTSQANPEALSAPALQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCLRVPRNNPDALGDVEGVPYSVLEPVLEGWTPDQLYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYDASRRQEKSAGAADPGNGEMEPAPKPAGSSQAPSGLGDGDGGSVSGGGSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYKGRFSRR
PTMs - Q8NG57 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K21 | Acetylation | Uniprot | |
| K26 | Methylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| T447 | Phosphorylation | Uniprot | |
| S503 | Phosphorylation | Uniprot | |
| S505 | Phosphorylation | Uniprot |
Research Backgrounds
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Nucleus.
Widely expressed.
Heterotrimer of an A (ELOA, ELOA2 or ELOA3), ELOB and ELOC subunit.
The BC-box, which mediates binding to the elongin BC complex, has the consensus sequence [APST]-L-x(3)-C-x(3)-[AILV].
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