KLF7 Antibody - #DF3636
Product: | KLF7 Antibody |
Catalog: | DF3636 |
Description: | Rabbit polyclonal antibody to KLF7 |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
Mol.Wt.: | 41 KD; 33kD(Calculated). |
Uniprot: | O75840 |
RRID: | AB_2836008 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3636, RRID:AB_2836008.
Fold/Unfold
KLF7; KLF7_HUMAN; Krueppel like factor 7; Krueppel-like factor 7; Kruppel like factor 7; Ubiquitous krueppel like factor; Ubiquitous krueppel-like factor; UKLF;
Immunogens
- O75840 KLF7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75840 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T45 | Phosphorylation | Uniprot | |
T189 | Phosphorylation | Uniprot | |
S196 | Phosphorylation | Uniprot | |
S199 | Phosphorylation | Uniprot | |
S201 | Phosphorylation | Uniprot | |
T242 | Phosphorylation | Uniprot | |
T244 | Phosphorylation | Uniprot | |
K247 | Ubiquitination | Uniprot |
Research Backgrounds
Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation. Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin.
Nucleus.
Widely expressed.
Interacts with FBXO38.
The acidic N-terminal part may favor interaction with the basic domain of transcription factors.
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In KLF7, the motif is inactive.
Belongs to the krueppel C2H2-type zinc-finger protein family.
Restrictive clause
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