MRPL12 Antibody - #DF3657
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3657, RRID:AB_2836029.
Fold/Unfold
39S ribosomal protein L12; 39S ribosomal protein L12, mitochondrial; 5c5-2; FLJ60124; L12mt; MGC8610; mitochondrial; Mitochondrial ribosomal protein L12; MRP-L12; MRP-L31/34; MRPL12; MRPL7; MRPL7/L12; RM12_HUMAN; RPML12;
Immunogens
- P52815 RM12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLPAAARPLWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P52815 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K138 | Acetylation | Uniprot | |
| K142 | Acetylation | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| T194 | Phosphorylation | Uniprot |
Research Backgrounds
Associates with mitochondrial RNA polymerase to activate transcription.
Mitochondrion.
Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins (Probable). bL12m interacts with NOA1.
Belongs to the bacterial ribosomal protein bL12 family.
Research Fields
· Genetic Information Processing > Translation > Ribosome.
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