KAL1 Antibody - #DF3780
| Product: | KAL1 Antibody |
| Catalog: | DF3780 |
| Description: | Rabbit polyclonal antibody to KAL1 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Sheep, Dog |
| Mol.Wt.: | 76 KD; 76kD(Calculated). |
| Uniprot: | P23352 |
| RRID: | AB_2836137 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3780, RRID:AB_2836137.
Fold/Unfold
Adhesion molecule-like X-linked; ADMLX; Anosmin-1; HHA; KAL; KAL1; KALIG 1; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome 1 sequence; Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS; OTTHUMP00000022873;
Immunogens
- P23352 KALM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVPGVPGAVLTLCLWLAASSGCLAAGPGAAAARRLDESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDLRKHQCQSFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVWDLPEEPDIPVHHYKVFWSWMVSSKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTSTHATNNKEQLVKTRKGGIQTQLPFQRRRPTRPLEVGAPFYQDGQLQVKVYWKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEAVFFTTPPCSALKGKSHKPVGCLGEAGHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGEGPATIKTFRTPELPPSSAHRSHLKHRHPHHYKPSPERY
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P23352 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S211 | Phosphorylation | Uniprot | |
| Y217 | Phosphorylation | Uniprot | |
| Y259 | Phosphorylation | Uniprot | |
| K339 | Acetylation | Uniprot | |
| T344 | Phosphorylation | Uniprot | |
| T450 | Phosphorylation | Uniprot | |
| Y579 | Phosphorylation | Uniprot | |
| T652 | Phosphorylation | Uniprot | |
| S676 | Phosphorylation | Uniprot |
Research Backgrounds
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells.
N-glycosylated.
May be proteolytically cleaved at the cell surface and released from the cell surface.
Cell membrane>Peripheral membrane protein. Secreted.
Note: Proteolytic cleavage may release it from the cell surface into the extracellular space.
Expressed in the cerebellum (at protein level).
Interacts with FGFR1; this interaction does not interfere with FGF2-binding to FGFR1. Binds heparin. Heparin may promote or interfere with ANOS1-FGFR1-FGF2 complex formation depending on the sequential order of its binding to the various constituents. For instance, heparin-ANOS1 interaction favors subsequent binding to pre-existing binary FGFR1-FGF2 complex, while heparin-FGF2 complex does not interact with ANOS1-FGFR1.
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