ARSI Antibody - #DF3798
| Product: | ARSI Antibody |
| Catalog: | DF3798 |
| Description: | Rabbit polyclonal antibody to ARSI |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 64 KD; 64kD(Calculated). |
| Uniprot: | Q5FYB1 |
| RRID: | AB_2836155 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3798, RRID:AB_2836155.
Fold/Unfold
Arylsulfatase family, member I; arylsulfatase I; ASI; EC 3.1.6; FLJ16069; SPG66;
Immunogens
- Q5FYB1 ARSI_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5FYB1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y252 | Phosphorylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| T302 | Phosphorylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot |
Research Backgrounds
Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts.
The oxidation of Cys-93 residue to 3-oxoalanine (also known as C(alpha)-formylglycine) by SUMF1/Sulfatase-modifying factor 1, seems critical for catalytic activity.
Secreted. Endoplasmic reticulum.
Note: Localized in the intracellular granular structures.
Expressed in placenta, in embryonic stem cells, fetal eyes and lens.
Belongs to the sulfatase family.
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